产品货号：
Z21872
中文名称：
NUB1抗体
英文名称：
Anti-NUB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NUB1 Antibody |
| 指标别名 | NEDD8 ultimate buster 1;NUB1;BS4;NUB1L;NYREN18 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM(Intracellular),ELISA |
| 基因名称 | NUB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NUB1 recombinant protein (Position:K190-D543). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NEDD8 ultimate buster 1 is a protein that in humans is encoded by the NUB1 gene.This gene encodes a protein that functions as a negative regulator of NEDD8,a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events.The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation.This protein interacts with the product of the AIPL1 gene,which is associated with Leber congenital amaurosis,an inherited retinopathy,and mutations in that gene can abolish interaction with this protein,which may contribute to the pathogenesis.This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies,and in glial cytoplasmic inclusions in multiple system atrophy,with this abnormal accumulation being specific to alpha-synucleinopathy lesions.Alternative splicing of this gene results in multiple transcript variants. |
| Uniprot ID | Q9Y5A7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | negative regulator of ubiquitin like proteins 1 |
| 蛋白名全称 | NEDD8 ultimate buster 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 4682 |
相关搜索：NUB1抗体，NUB1多抗，Anti-NUB1 Antibody